tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate
CAS: 857898-70-5
Molecular Formula: C18H26N2O2
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate - Names and Identifiers
| Name | tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate |
| Synonyms | TERT-BUTYL 1H-SPIRO[ISOQUINOLINE-4,4'-PIPERIDINE]-2(3H)-CARBOXYLATE tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate tert-butyl spiro[1,3-dihydroisoquinoline-4,4-piperidine]-2-carboxylate tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-2-carboxylate Spiro[isoquinoline-4(1H),4'-piperidine]-2(3H)-carboxylic acid tert-butyl ester Spiro[isoquinoline-4(1H),4'-piperidine]-2(3H)-carboxylic acid, 1,1-dimethylethyl ester |
| CAS | 857898-70-5 |
| InChI | InChI=1/C18H26N2O2/c1-17(2,3)22-16(21)20-12-14-6-4-5-7-15(14)18(13-20)8-10-19-11-9-18/h4-7,19H,8-13H2,1-3H3 |
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate - Physico-chemical Properties
| Molecular Formula | C18H26N2O2 |
| Molar Mass | 302.41 |
| Density | 1.13 |
| Boling Point | 428℃ |
| Flash Point | 213℃ |
| Vapor Presure | 1.57E-07mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.57 |
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate - Risk and Safety
| HS Code | 29334900 |
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate - Introduction
tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate is an organic compound. Here is the relevant information about the compound:
Nature:
-Appearance: colorless or light yellow liquid
-Molecular formula: C21H27NO2
-Molecular weight: 325.45g/mol
-Melting point: about 25 ℃
-Boiling point: about 458 ℃
-Solubility: Soluble in ethanol, ethers and organic solvents
Use:
- tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate is widely used as an intermediate in organic synthetic chemistry.
-It can be used to synthesize drugs containing isoquinoline and piperidine groups, such as certain antipsychotic drugs and anticancer drugs.
Preparation Method:
- tert-Butyl The preparation of 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate can be accomplished by synthetic procedures. A common method is the reaction of isoquinolin-4-one and piperidine ammonium bromide with tert-butanol under chemical reaction conditions to produce the target product.
Safety Information:
-When using and storing tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate, care should be taken to prevent contact with eyes, skin and respiratory tract. Appropriate personal protective equipment, such as goggles, gloves and face shields, should be worn.
-The compound should be used in a well-ventilated area and smoking, eating and drinking are prohibited.
-When storing, keep it in a sealed container, away from fire and oxidizing agents.
Please note that this is only a general introduction to the tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate. The specific preparation method and safe operation should follow the regulations and instructions of relevant chemical laboratories.
Nature:
-Appearance: colorless or light yellow liquid
-Molecular formula: C21H27NO2
-Molecular weight: 325.45g/mol
-Melting point: about 25 ℃
-Boiling point: about 458 ℃
-Solubility: Soluble in ethanol, ethers and organic solvents
Use:
- tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate is widely used as an intermediate in organic synthetic chemistry.
-It can be used to synthesize drugs containing isoquinoline and piperidine groups, such as certain antipsychotic drugs and anticancer drugs.
Preparation Method:
- tert-Butyl The preparation of 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate can be accomplished by synthetic procedures. A common method is the reaction of isoquinolin-4-one and piperidine ammonium bromide with tert-butanol under chemical reaction conditions to produce the target product.
Safety Information:
-When using and storing tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate, care should be taken to prevent contact with eyes, skin and respiratory tract. Appropriate personal protective equipment, such as goggles, gloves and face shields, should be worn.
-The compound should be used in a well-ventilated area and smoking, eating and drinking are prohibited.
-When storing, keep it in a sealed container, away from fire and oxidizing agents.
Please note that this is only a general introduction to the tert-Butyl 1H-spiro[isoquinoline-4,4 '-piperidine]-2(3H)-carboxylate. The specific preparation method and safe operation should follow the regulations and instructions of relevant chemical laboratories.
Last Update：2024-04-09 19:05:52
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CAS: 857898-70-5
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CAS: 857898-70-5
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Product Name: Spiro[isoquinoline-4(1H),4'-piperidine]-2(3H)-carboxylic acid tert-butyl ester Visit Supplier Webpage Request for quotation
CAS: 857898-70-5
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CAS: 857898-70-5
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